Regenerative medicine in orthopedics: advances in biomaterials and cell therapies

Regenerative medicine in orthopedics: advances in biomaterials and cell therapies

Authors

  • Fernanda Cristina Galerani Gualtieri Parpinelli Author
  • João Marcos Laskoski Author
  • Mhayra de Almeida Sousa Author
  • André Williams Bazzo Fernandes Author
  • Fernanda Yoshiko Souza Nishi Author
  • Cássia Letícia da Silva Author
  • Augustin Malzac Author

DOI:

https://doi.org/10.51473/rcmos.v1i2.2025.1474

Keywords:

Regenerative medicine. Biomaterials. Cell therapies. Orthopedics. Nanotechnology.

Abstract

This article presents a literature review on the advances of regenerative medicine applied to orthopedics, focusing on the use of biomaterials, cell therapies, and nanotechnology for bone and cartilage regeneration. Studies published between 2012 and 2022 were analyzed, highlighting the application of scaffolds, hydrogels, polymers, ceramics, and cell therapies, including mesenchymal stem cells and induced pluripotent stem cells. The results indicate a promising future, but with challenges related to standardization, safety, and regulation.

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Author Biographies

  • Fernanda Cristina Galerani Gualtieri Parpinelli

    – Universidade Federal de Mato Grosso do Sul (UFMS)

  • João Marcos Laskoski

     - Universidade Federal de Mato Grosso do Sul (UFMS)

  • Mhayra de Almeida Sousa

     - Universidade Federal de Mato Grosso do Sul (UFMS)

  • André Williams Bazzo Fernandes

    - Universidade Federal de Mato Grosso do Sul (UFMS)

  • Fernanda Yoshiko Souza Nishi

    - Universidade Federal de Mato Grosso do Sul (UFMS)

  • Cássia Letícia da Silva

    - Universidade Federal de Mato Grosso do Sul (UFMS)

  • Augustin Malzac

     – Médico Ortopedista /Docente na Universidade Federal do Mato Grosso do Sul (UFMS)

References

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Published

2025-10-06

How to Cite

PARPINELLI , Fernanda Cristina Galerani Gualtieri; LASKOSKI, João Marcos; SOUSA, Mhayra de Almeida; FERNANDES , André Williams Bazzo; NISHI , Fernanda Yoshiko Souza; SILVA , Cássia Letícia da; MALZAC, Augustin. Regenerative medicine in orthopedics: advances in biomaterials and cell therapies: Regenerative medicine in orthopedics: advances in biomaterials and cell therapies. Multidisciplinary Scientific Journal The Knowledge, Brasil, v. 1, n. 2, 2025. DOI: 10.51473/rcmos.v1i2.2025.1474. Disponível em: https://submissoesrevistarcmos.com.br/rcmos/article/view/1474. Acesso em: 10 oct. 2025.