Prevalence of hemophilia a and b and the distribution of factor viii concentrate in Brazil

Prevalence of hemophilia a and b and the distribution of factor viii concentrate in Brazil

Authors

  • Erika Aparecida de Moura Silva Author
  • Thauana Batista Fuchs Loureiro Author
  • Walace Rocha Author

DOI:

https://doi.org/10.51473/rcmos.v1i2.2025.1406

Keywords:

Hemophilia A. Hemophilia B. Factor VIII.

Abstract

Hemophilia is an inherited bleeding disorder caused by deficiencies in clotting factors VIII or IX due to genetic mutations. Brazil ranks fourth worldwide in prevalence, with approximately 12,400 individuals affected, 36.1% of whom have severe forms. This study aims to assess the prevalence of hemophilia A and B in Brazil during 2021, using data from the Hemovida Web Coagulopathies platform. Additionally, it seeks to correlate these data with the distribution of factor VIII concentrate by region, state, sex, and age. The methodology used was descriptive, with statistical analysis of diagnoses and treatment distribution, aiming to identify disparities in access to therapy and to contribute to the improvement of public policies aimed at rare diseases.

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Author Biographies

  • Erika Aparecida de Moura Silva

    Graduada em Biomedicina pela Universidade do Oeste Paulista (UNOESTE), Guarujá, SP, Brasil.

  • Thauana Batista Fuchs Loureiro

    Graduada em Biomedicina pela Universidade do Oeste Paulista (UNOESTE), Guarujá, SP, Brasil.

  • Walace Rocha

    - Orientador

References

PIO, S. F.; OLIVEIRA, G. C. de; REZENDE, S. M. As bases moleculares da hemofilia A. Revista da Associação Médica Brasileira, v. 55, n. 2, p. 213–219, 2009. DOI: https://doi.org/10.1590/S0104-42302009000200029

CAIO, V. M. et al. Genética comunitária e hemofilia em uma população brasileira. Cadernos de Saúde Pública, v. 17, n. 3, p. 595–605, 2001. DOI: https://doi.org/10.1590/S0102-311X2001000300014

SAYAGO, M.; LORENZO, C. O acesso global e nacional ao tratamento da hemofilia: reflexões da bioética crítica sobre exclusão em saúde. Interface, v. 24, e180722, 2020. DOI: https://doi.org/10.1590/interface.180722

MINISTÉRIO DA SAÚDE (BR). Dados de Coagulopatias 2021. Brasília: Ministério da Saúde, 2021.

RODRIGUES, S. H. L. Perfil de utilização de medicamentos pró-coagulantes bypassing disponibilizados no SUS para tratamento das coagulopatias, Brasil. 2021.

Published

2025-09-17

How to Cite

SILVA, Erika Aparecida de Moura; LOUREIRO, Thauana Batista Fuchs; ROCHA , Walace. Prevalence of hemophilia a and b and the distribution of factor viii concentrate in Brazil: Prevalence of hemophilia a and b and the distribution of factor viii concentrate in Brazil. Multidisciplinary Scientific Journal The Knowledge, Brasil, v. 1, n. 2, 2025. DOI: 10.51473/rcmos.v1i2.2025.1406. Disponível em: https://submissoesrevistarcmos.com.br/rcmos/article/view/1406. Acesso em: 10 oct. 2025.