The integration of precision nutritional therapy in oncology care: protocol standardization, tumor metabolism, and economic sustainability in Healthcare systems
The integration of precision nutritional therapy in oncology care: protocol standardization, tumor metabolism, and economic sustainability in Healthcare systems
DOI:
https://doi.org/10.51473/rcmos.v1i2.2024.1838Keywords:
Oncological Nutrition. Tumor Metabolism. Clinical Protocols. Cachexia. Healthcare Management.Abstract
This scientific article proposes an exhaustive analysis of the intersection between the pathophysiology of oncological metabolism and the strategic management of healthcare services. Grounded in the author's academic background in Health Sciences, with an emphasis on Surgery, Nutrition, and Metabolism, the study investigates the molecular mechanisms of neoplastic cachexia and advocates for an intervention model based on the standardization of high-complexity nutritional protocols. The research demonstrates that oncological malnutrition is not merely a consequence of the disease but a determinant factor in the interruption of chemotherapeutic treatments and the increase in hospital costs. Through a critical review of the literature up to the year 2022, it discusses how the implementation of evidence-based guidelines (ASPEN, ESPEN) and technical training of multidisciplinary teams can reduce the progression of sarcopenia and attenuate immunosuppression, contributing to a better treatment response. The work concludes that specialized nutritional management, combined with innovation and technical training, constitutes an indispensable tool for the economic sustainability of healthcare systems, aligning superior clinical outcomes with the operational efficiency required in the contemporary healthcare landscape.
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ARENDS, J. et al. ESPEN guidelines on nutrition in cancer patients. Clinical Nutrition, v. 36, n. 1, p. 11-48, 2017. DOI: https://doi.org/10.1016/j.clnu.2016.07.015
BARACOS, V. E. et al. Cancer-associated cachexia. Nature Reviews Disease Primers, v. 4, n. 1, p. 1-18, 2018. DOI: https://doi.org/10.1038/nrdp.2017.105
FEARON, K. et al. Definition and classification of cancer cachexia: an international consensus. The Lancet Oncology, v. 12, n. 5, p. 489-495, 2011. DOI: https://doi.org/10.1016/S1470-2045(10)70218-7
LAVIANO, A.; KORETZ, R. L. Nutrition in cancer patients. Nature Reviews Cancer, v. 20, n. 1, p. 55-67, 2020.
MUSCARITOLI, M. et al. ESPEN practical guideline: clinical nutrition in cancer. Clinical Nutrition, v. 40, n. 5, p. 2898-2913, 2021. DOI: https://doi.org/10.1016/j.clnu.2021.02.005
PRADO, C. M. et al. Sarcopenia and cachexia in the era of obesity: clinical and nutritional relevance. Proceedings of the Nutrition Society, v. 75, n. 2, p. 188-198, 2016. DOI: https://doi.org/10.1017/S0029665115004279
WEIMANN, A. et al. ESPEN guideline: clinical nutrition in surgery. Clinical Nutrition, v. 36, n. 3, p. 623-650, 2017. DOI: https://doi.org/10.1016/j.clnu.2017.02.013
ZHANG, X. et al. The role of inflammation in the pathogenesis of cancer cachexia. Journal of Cellular Physiology, v. 234, n. 5, p. 5664-5672, 2019.
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Copyright (c) 2024 Suzana Souza Arantes Lanzieri (Autor)
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