The interface between psychoneuroimmunology and behavioral management: an analysis of inflammatory biomarkers and the impact of emotional intelligence on corporate health
The interface between psychoneuroimmunology and behavioral management: an analysis of inflammatory biomarkers and the impact of emotional intelligence on corporate health
DOI:
https://doi.org/10.51473/rcmos.v1i1.2025.1923Keywords:
Psychoneuroimmunology. Clinical Hematology. TNF-α. Emotional Intelligence. Corporate Health.Abstract
This scientific article proposes a transdisciplinary analysis connecting clinical hematology, immunogenetics, and behavioral neuroscience to understand the phenomenon of occupational stress and burnout. Based on the premise that deregulated emotional states trigger measurable inflammatory cascades, the study revisits the role of pro-inflammatory cytokines, such as Tumor Necrosis Factor alpha (TNF-α), and their modulation through genetic polymorphisms, correlating them to individual susceptibility to stress. From this biological basis, it investigates how interventions based on Emotional Intelligence and Positive Psychology act as neuroendocrine regulation mechanisms capable of mitigating systemic inflammatory response. The research suggests a new model of corporate management, where the diagnosis of organizational health integrates biological and behavioral markers, proposing human development training not only as productivity tools but as preventive public health interventions.
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BONIFÁCIO, L. G.; MELO, M. et al. TNFα rs1799964 TT genotype may be a susceptibility factor for vertical transmission of Toxoplasma gondii and clinical signs in newborns from pregnant women with acute toxoplasmosis. Molecular Biology Reports, v. 49, p. 4759-4768, 2022. DOI: https://doi.org/10.1007/s11033-022-07327-y
DAMÁSIO, A. O. O erro de Descartes: emoção, razão e o cérebro humano. São Paulo: Companhia das Letras, 2012.
GOLEMAN, D. Inteligência emocional: a teoria revolucionária que redefine o que é ser inteligente. Rio de Janeiro: Objetiva, 2012.
KANDEL, E. R. et al. Principles of neural science. 5. ed. New York: McGraw-Hill, 2013.
SAPOLSKY, R. M. Why zebras don’t get ulcers: the acclaimed guide to stress, stress-related diseases, and coping. 3. ed. New York: Henry Holt and Company, 2004.
SEGERSTROM, S. C.; MILLER, G. E. Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry. Psychological Bulletin, v. 130, n. 4, p. 601-630, 2004. DOI: https://doi.org/10.1037/0033-2909.130.4.601
STERNBERG, E. M. The balance within: the science connecting health and emotions. New York: W. H. Freeman, 2001.
TILLICH, P. Teologia da cultura. São Paulo: Fonte Editorial, 2009.
ABBAS, A. K.; LICHTMAN, A. H.; PILLAI, S. Imunologia celular e molecular. 9. ed. Rio de Janeiro: Elsevier, 2019.
MAES, M. et al. Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways. BMC Medicine, v. 10, n. 66, 2012. DOI: https://doi.org/10.1186/1741-7015-10-66
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Copyright (c) 2025 Mirele Melo (Autor)

This work is licensed under a Creative Commons Attribution 4.0 International License.


