Perihilar cholangiocarcinoma: case report and surgical approach
Perihilar cholangiocarcinoma: case report and surgical approach
DOI:
https://doi.org/10.51473/rcmos.v1i1.2026.2005Keywords:
Cholangiocarcinoma, Biliary neoplasms, Hepatic surgeryAbstract
Cholangiocarcinoma is a rare and aggressive malignant neoplasm arising from the biliary epithelium. Diagnosis is often delayed due to nonspecific symptoms. We report the case of a 59-year-old female presenting with epigastric and right upper quadrant pain for one year, associated with postprandial nausea and vomiting, without jaundice or weight loss. Laboratory tests showed mild hyperbilirubinemia and normal tumor markers. Computed tomography and magnetic resonance cholangiography revealed an infiltrative lesion in hepatic segment IV with intraductal extension involving the hepatic hilum, classified as Bismuth-Corlette IIIB. Liver biopsy confirmed moderately differentiated adenocarcinoma. The patient underwent partial hepatectomy with lymphadenectomy of the hepatic pedicle, achieving tumor-free margins. Postoperative recovery was uneventful. Surgical resection with curative intent remains the cornerstone of treatment when feasible.
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CARINGI, Silvio et al. Hot topics in the surgical treatment of intrahepatic cholangiocarcinoma: a narrative review of current managements. Cancers, Basel, v. 17, n. 3, p. 127, 2025. DOI: 10.3390/cancers1703127. Disponível em: https://www.mdpi.com/2072-6694/17/3/127. Acesso em: 02 fev. 2026.
LIGUORI, Carolina et al. Is it a new era for intrahepatic cholangiocarcinoma? Critical Reviews in Oncology/Hematology, Amsterdam, v. 215, p. 104923, 2025. DOI: 10.1016/j.critrevonc.2025.104923. Disponível em: https://www.sciencedirect.com. Acesso em: 02 fev. 2026. DOI: https://doi.org/10.1016/j.critrevonc.2025.104923
COLANGELO, Matteo et al. Management of intrahepatic cholangiocarcinoma: a review for clinicians. Gastroenterology Report, Oxford, v. 13, p. goaf005, 2025. DOI: 10.1093/gastro/goaf005. Disponível em: https://academic.oup.com. Acesso em: 02 fev. 2026. DOI: https://doi.org/10.1093/gastro/goaf005
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Copyright (c) 2026 Lucas Rocha da Silva, Brigida Thaine Fernandes Cabral, Danielle Alcântara Barbosa Macedo (Autor)

This work is licensed under a Creative Commons Attribution 4.0 International License.

